Sulfonylurea Hypoglycemics Drug Levels
Label Mnemonic: SUREAS
Epic Lab Code: LAB4113
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Preferred Minimum: 1 mL serum
Absolute Minimum: 0.4 mL serum
Rejection Criteria:
Separator tubes.
Turn Around Time:
1-6 days upon receipt at reference laboratory
Reference Range:
Drug Cutoff Concentration Glyburide 5 ng/mL Glimepiride 5 ng/mL Glipizide 5 ng/mL Repaglinide 5 ng/mL Nateglinide 5 ng/mL Acetohexamide 100 ng/mL Chlorpropamide 100 ng/mL Tolazamide 100 ng/mL Tolbutamide 100 ng/mL
Interpretive Data:
This assay is used to evaluate hypoglycemia that may be caused from the ingestion of sulfonylurea drugs. Hypoglycemic drugs are detected (present) in this assay if the drug concentration is greater than the limit of detection (cut-off). The presence of hypoglycemic drug(s) indicates a recent ingestion.
Comments:
Preferred test for evaluating if etiology of hypoglycemia is sulfonylurea ingestion.
Methodology:
Qualitative Liquid Chromatography-Tandem Mass Spectrometry
CPT Code:
80377