Cadmium
Label Mnemonic: CDB
Epic Lab Code: LAB2772
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Blood
Specimen Instructions:
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician).
Collection Medium:
Royal Blue K2 EDTA tube
Minimum:
Adult Minimum: 7.0 mL whole blood from Royal Blue (K2 EDTA) tube
Absolute Minimum: 0.5 mL whole blood from Royal Blue (K2 EDTA) tube
Rejection Criteria:
Heparin anticoagulant. Frozen specimens.
Turn Around Time:
1-3 days upon receipt at reference laboratory
Reference Range:
0.0 - 5.0 μg/L
Interpretive Data:
Blood cadmium levels can be used to monitor acute toxicity and in combination with cadmium urine and B-2 microglobulin is the preferred method for monitoring occupational exposure. Symptoms associated with cadmium toxicity vary based upon route of exposure and may include tubular proteinuria, fever, headache, dyspnea, chest pain, conjunctivitis, rhinitis, sore throat and cough. Ingestion of cadmium in high concentration may cause vomiting, diarrhea, salivation, cramps, and abdominal pain.
Comments:
Royal Blue trace metal tube available from the Clinical Pathology Core Laboratory, 6240 RCP.
Test Limitations:
Elevated results from noncertified trace element-free collection tubes may be due to contamination. Elevated concentrations of trace elements in blood should be confirmed with a second specimen collected in a tube designed for trace element determinations, such as a royal blue Na2EDTA tube.
Methodology:
Quantitative Inductively Coupled Plasma/Mass Spectrometry
CPT Code:
82300