Benzodiazepine, Conf

Label Mnemonic:	BENZOC
Epic code:	LAB368
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Random Urine

Collection Medium:

Clear top tube

Minimum:

Preferred Minimum: 0.5 mL random urine with no additives or preservatives
Absolute Minimum: 0.3 mL random urine with no additives or preservatives

Rejection Criteria:

Specimens exposed to repeated freeze/thaw cycles.

Turn Around Time:

1-4 days upon receipt at reference laboratory

Reference Range:

Drugs Covered            Cutoff Concentrations
Alprazolam                      5 ng/mL
Alpha-hydroxyalprazolam         5 ng/mL
Chlordiazepoxide               20 ng/mL
Clonazepam                      5 ng/mL
7-aminoclonazepam               5 ng/mL
Diazepam                       20 ng/mL
Lorazepam                      20 ng/mL
Midazolam                      20 ng/mL
Alpha-hydroxymidazolam         20 ng/mL
Nordiazepam                    20 ng/mL
Oxazepam                       20 ng/mL
Temazepam                      20 ng/mL

Interpretive Data:

Drugs covered: alprazolam, alpha-hydroxyalprazolam, chlordiazepoxide, clonazepam, 7-aminoclonazepam, diazepam, lorazepam, midazolam, alpha-hydroxymidazolam, nordiazepam, oxazepam and temazepam.

Positive cutoff: 20 ng/mL unless specified below:
Alprazolam 5 ng/mL
Alpha-hydroxyalprazolam 5 ng/mL
Clonazepam 5 ng/mL
7-aminoclonazepam 5 ng/mL

For medical purposes only; not valid for forensic use.

Identification of specific drug(s) taken by specimen donor is problematic due to common metabolites, some of which are prescription drugs themselves. The absence of expected drug(s) and/or drug metabolite (s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

Methodology:

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

CPT Code:

80346

See Additional Information:
Urine Tests Requiring no Preservatives