Copper
| Label Mnemonic: | CUU |
| Epic code: | LAB380 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
24 hr Urine More information
Specimen
Instructions:
Refrigerate during 24 hr collection in plastic container.
Reference laboratory studies indicate that refrigeration of
urine alone, during and after collection, preserves specimens
adequately, if tested within 14 days of collection.
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). Collection from patients receiving iodinated or gadolinium-based contrast media must be avoided for a minimum of 72 hours post-exposure. Collection from patients with impaired kidney function should be avoided for a minimum of 14 days post contrast media exposure.
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). Collection from patients receiving iodinated or gadolinium-based contrast media must be avoided for a minimum of 72 hours post-exposure. Collection from patients with impaired kidney function should be avoided for a minimum of 14 days post contrast media exposure.
Collection Medium:
) |
| Urine - 24 hour/timed plastic urine container |
Minimum:
Preferred Minimum: 8 mL urine from a well-mixed, refrigerated, 24 hr
urine collection.
Absolute Minimum: 1 mL urine from a well-mixed, refrigerated, 24 hr urine collection.
Absolute Minimum: 1 mL urine from a well-mixed, refrigerated, 24 hr urine collection.
Rejection Criteria:
Specimens collected within 72 hours after administration of iodinated or gadolinium-based contrast media. Acid preserved urine. Specimens transported in containers other than specified. Specimens contaminated with blood or fecal material.
Turn Around
Time:
1-5 days upon receipt at reference laboratory
Reference Range:
Copper, Urine-per volume: Less than or equal to 3.2 µg/dL Copper, Urine-per 24-hour: 3.0-45.0 μg/d Copper, Urine-ratio to CRT: 10.0-45.0 μg/gCRT Creatinine, Urine - per 24-hour Male 3-8 years: 140-700 mg/d 9-12 years: 300-1300 mg/d 13-17 years: 500-2300 mg/d 18-50 years: 1000-2500 mg/d 51-80 years: 800-2100 mg/d 81 years and older: 600-2000 mg/d Female 3-8 years: 140-700 mg/d 9-12 years: 300-1300 mg/d 13-17 years: 400-1600 mg/d 18-50 years: 700-1600 mg/d 51-80 years: 500-1400 mg/d 81 years and older: 400-1300 mg/d Copper per gram of creatinine - No reference interval (μg/g crt)
Interpretive Data:
Individuals with symptomatic Wilson disease usually excrete more than
100 ug copper per day. Other conditions associated with elevated urine
copper include cholestatic liver disease, proteinuria, some
medications, and contaminated specimens. Although random specimens
may
contain diagnostic information, a 24-hour collection is a more
consistent indicator of copper urine.
Methodology:
Quantitative Inductively Coupled Plasma-Mass Spectrometry
CPT Code:
82525
See Additional Information:
Urine Tests Requiring Preservatives, Refrigeration or Special Containers
Urine Tests Requiring Preservatives, Refrigeration or Special Containers