Clonazepam Drug Level

Label Mnemonic:	CLON
Epic code:	LAB466
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Specimen Instructions:

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 2.0 mL serum
Absolute Minimum: 1.0 mL serum

Rejection Criteria:

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate).

Turn Around Time:

1-7 days upon receipt at reference laboratory.

Reference Range:

Dose-Related Range:
     20 - 70 ng/mL   Dose (Adult) 1 - 8 mg per day

Toxic = > 80 ng/mL

Interpretive Data:

Adverse effects may include drowsiness, headache, fatigue and ataxia.

Methodology:

Quantitative Liquid Chromatography/Tandem Mass Spectrometry

CPT Code:

80346