Clomipramine & Metabolite Drug Level
Label Mnemonic: CLOM
Epic code: LAB2880
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
Collection Medium:
Red top tube 5 mL (Clot Activator)
Preferred Minimum: 1.0 mL serum
Rejection Criteria:
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Delivery Instructions:
Deliver to laboratory within 1 hour of collection.
Turn Around Time:
1-5 days upon receipt in reference laboratory.
Reference Range:
Therapeutic Range:
 Total clomipramine and norclomipramine:  220 - 500 ng/mL

Toxic: > 900 ng/mL
Interpretive Data:
The therapeutic range listed relates to the antidepressant characteristics of the drug. A therapeutic range for treating obsessive compulsive disorder is not well established. Toxic concentrations may cause anticholinergic effects, CNS depression, cardiac abnormalities, seizures and hypotension.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
CPT Code: