Chloride
Label Mnemonic: CL
Epic Lab Code: LAB59
Downtime Form: A-1a General Laboratory Requisition
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood from light green top tube or 1 Microtainer® for pediatric patients
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
95-107 mEq/l
Test Limitations:
Patients over a wide anion gap range demonstrated no significant chloride bias from coulometric titrations. Bromide at 0.7 mmol/l gave a 1 mmol/l chloride response (4). Selectivity of chloride cartridge (mmol/l of anion required to increase chloride results by 1 mmol/l) (4). A list of substances and conditions known to affect the level of sodium, potassium or chloride in vivo is given by both Young et al (5) and Friedman et al (6). No representation is made by Roche Diagnostics regarding the completeness of these lists or the accuracy of the information contained therein. Hemolysis: No significant interference up to an H index of 1000. Icterus: No significant interference up to an I index of 60 (approximate conjugated and unconjugated bilirubin concentration: 60 mg/dL). Lipemia: No significant interference up an L index of 2000. References: (1) Glick MR, Ryder KW, Glick SJ. Interferographs: Users Guide to Interferences in Clinical Chemistry Instruments, 2nd ed. Indianapolis, IN: Science Enterprises Inc; 1991:35-44. (2) Tietz NW. Fundamentals of Clinical Chemistry. Philadelphia, Pa: 3rd ed. WB Saunders Co; 1987:617. (3) Tietz NW. Clinical Chemistry. Philadelphia, Pa: 2nd ed.,WB Saunders Co; 1994:1356, 1364, 1365. (4) Simmons M, Sugahara K, Watanabe M. Development of an Improved Chloride Electrode for the Boehringer Mannheim/Hitachi 700 Series Analyzers. Poster session presented at the 1988 National Meeting of the American Association for Clinical Chemistry, New Orleans, LA, July 27, 1988 (reprints available from Roche Diagnostics Corporation). (5) Young DS, et al. Clin Chem. 1975;21, No 5. (6) Friedman RB, et al. Clin Chem. 1980;26, No 4.
Methodology:
Ion Selective Electrode
CPT Code:
82435
 
See also:
Chloride-Other, Body Fluid