Chromogenic Factor VIII Inhibitor (Mailout)
Label Mnemonic: F8INH
Epic code: LAB9192
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mailout Laboratory
6240-8 RCP
356-8593
Specimen(s):
Plasma
Specimen Instructions:
Hand specimen to Coag/Heme staff for centrifugation. Spin and remove top 2/3 and spin AGAIN. Aliquot 1.5 mL platelet poor plasma (Min: 1.0 mL).
Collection Medium:
Light Blue top tube 2.7 mL (Na Citrate)
Minimum:
Preferred Minimum: 1.5 mL platelet-poor plasma
Absolute Minimum: 1 mL platelet-poor plasma
Delivery Instructions:
CRITICAL FROZEN. Freeze immediately. Separate specimens must be submitted when multiple tests are ordered.
Turn Around Time:
7 working days upon receipt at reference laboratory
Comments:
The chromogenic factor VIII inhibitor assay uses bovine reagents, is insensitive to emicizumab and lupus anticoagulant, and is adversely affected by the presence of direct factor X inhibitors or high concentrations of heparin.
Methodology:
Chromogenic Bethesda Titer
CPT Code:
85335