NPM1 Mutation Quantitative, MRD Monitoring and Interpretation
| Label Mnemonic: | NPM1QNT |
| Epic code: | LAB8828 |
| Downtime form: | A-1a Doctor/Provider Orders - Pathology Molecular |
Molecular Pathology
6240 RCP
384-9568
6240 RCP
384-9568
Specimen(s):
Whole Blood
Specimen
Instructions:
Testing requires dedicated collection tube.
DO NOT CENTRIFUGE. Store and send whole blood refrigerated.
DO NOT CENTRIFUGE. Store and send whole blood refrigerated.
Collection Medium:
 |
| Pink top tube 6 mL (K2-EDTA) |
Minimum:
5.0 mL Whole Blood in EDTA anti-coagulated pink top tube
Delivery Instructions:
Deliver to laboratory immediately after collection.Turn Around
Time:
10-14 days upon receipt in laboratory
Methodology:
The NPM1 Mutation Quantitation assay uses multiplex reverse
transcription in combination with droplet digital PCR technology. The
type A NPM1 duplications occur in most AML cases. The assay can
reliably detect 1 tumor cell in a background of 20,000 normal cells.
The limit of quantitation is 0.005% NPM1/ABL1 ratio.
CPT Code:
81310