Aqueous Fluid or Vitreous Fluid

Preferred Minimum: 0.1 mL Aqueous or Vitreous Fluid
Absolute Minimum: 0.05 mL Aqueous or Vitreous Fluid

Do not add water, saline or other fluid media to container. Do not ship specimen in syringe.

Ship Monday through Friday. Friday shipments must be labeled for Saturday delivery. All specimens must be labeled with patient's name and collection date.

Within 8 - 12 hours upon receipt at reference laboratory

Cytomegalovirus (CMV) is an important pathogen in the transplant setting causing pneumonitis, colitis, hepatitis, CNS disease, neutropenia, and disseminated disease. Prior to the availability of rapid and sensitive DNA PCR, CMV was a leading cause of morbidity and mortality in the transplant population. Quantitative CMV DNA PCR can be used for early detection of CMV reactivation, primary infections, and monitoring response to treatment.

Clinically significant Cytomegalovirus infection frequently develops in immunocompromised patient populations (e.g. hematopoietic stem cell transplantation, solid organ transplant and HIV). A frequent complication after transplantation, CMV infection may cause a series of direct and indirect effects that lead to increased incidence of graft rejection, opportunistic infections, and decreased allograft and patient survival.1,2 Symptomatic CMV disease in immunocompromised individuals can affect almost every organ of the body, resulting in fever, pneumonia, hepatitis, encephalitis, myelitis, colitis, uveitis, retinitis, and neuropathy.

Extraction of CMV DNA from specimen followed by amplification and detection using real-time, quantitative PCR.

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