Phospholipase A2 Receptor (PLA2R) Antibody, IgG with Reflex to Titer

Label Mnemonic:	PLA2R
Epic code:	LAB8739
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1.0 mL serum in red top tube
Absolute Minimum: 0.2 mL serum in red top tube

Rejection Criteria:

Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated.

Turn Around Time:

1-8 days upon receipt at reference laboratory

Reference Range:

Less than 1:10

Interpretive Data:

A positive result (1:10 or greater) for phospholipase A2 receptor antibody, IgG, in conjunction with other laboratory and clinical findings, supports a diagnosis of primary membranous glomerulonephritis (pMGN).

Comments:

This test aids in the differential diagnosis of membranous glomerulonephritis (MGN) or nephrotic syndrome of unknown etiology.

Note: If Phospholipase A2 Receptor Antibody, IgG is positive, then a Phospholipase Receptor A2 Antibody, IgG titer is reported. Additional charges apply.

Methodology:

Semi-Quantitative Indirect Fluorescent Antibody

CPT Code:

86255; if titer performed, 86256