Autoimmune Liver Disease Panel
| Label Mnemonic: | ALDP |
| Epic code: | LAB8698 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
6240-8 RCP
356-8593
 |
| Red top tube 5 mL (Clot Activator) |
Preferred Minimum: 1.5 mL Serum
Absolute Minimum: 1.1 mL Serum
Monday through Friday; 9 am and 4 pm, Saturday; 12 pm
SMOOTH MUSCLE ANTIBODIES
Negative
If positive, results are titered.
Reference values apply to all ages
MITOCHONDRIAL ANTIBODIES (M2)
Negative: <0.1 Units
Borderline: 0.1-0.3 Units
Weakly positive: 0.4-0.9 Units
Positive: > or =1.0 Units
Reference values apply to all ages.
ANTINUCLEAR ANTIBODIES (ANA2)
Negative: < or =1.0 Units
Weakly positive: 1.1-2.9 Units
Positive: 3.0-5.9 Units
Strongly positive: > or =6.0 Units
Reference values apply to all ages.
The presence of smooth muscle antibodies (SMAs) and/or antinuclear antibodies (ANAs) is consistent with a diagnosis of chronic autoimmune hepatitis, in patients with clinical and/or laboratory evidence of hepatocellular damage.
The presence of anti-mitochondrial antibodies (AMAs) is consistent with a diagnosis of primary biliary cirrhosis, in patients with clinical and/or laboratory evidence of hepatobiliary damage.
AMA: Enzyme Immunoassay (EIA)
SMA: Indirect Immunofluorescence
ANA2: Enzyme-Linked Immunosorbent Assay (ELISA)
86256-Smooth Muscle Antibodies Titer (if appropriate)
Useful for:
Evaluation of patients with suspected autoimmune liver disease, specifically autoimmune hepatitis or primary biliary cirrhosis.
Evaluation of patients with liver disease of unknown etiology.