Chromogenic Factor VIII Assay
Label Mnemonic: CH8
Epic code: LAB8465
Downtime form: Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Hemostasis/Thrombosis
6240 RCP
356-3573
Specimen(s):
Plasma
Collection Medium:
Light Blue top tube 2.7 mL (Na Citrate)
Minimum:

Full draw; 2.7 mL light blue top

Rejection Criteria:  Short drawn tube, clot, traumatic tap (excessive hemolysis).

Delivery Instructions:
Deliver to laboratory immediately after collection.
Turn Around Time:

24–48 hours

Reference Range:

43–159%

Comments:

The chromogenic factor VIII activity assay utilizes bovine factor X and human thrombin and factor IXa. It is insensitive to emicizumab, but may yield unreliable results in the presence of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban), high concentrations of heparin (>2 IU/mL), strong lupus anticoagulants (ratio >1.8), or the Mim8 bispecific antibody.

Methodology:

Chromogenic

CPT Code:
85130