Chromogenic Factor VIII Assay
| Label Mnemonic: | CH8 |
| Epic code: | LAB8465 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Hemostasis/Thrombosis
6240 RCP
356-3573
6240 RCP
356-3573
Specimen(s):
Plasma
Collection Medium:
 |
| Light Blue top tube 2.7 mL (Na Citrate) |
Minimum:
Full draw; 2.7 mL light blue top
Rejection Criteria: Short drawn tube, clot, traumatic tap (excessive hemolysis).
Delivery Instructions:
Deliver to laboratory immediately after collection.Turn Around
Time:
24–48 hours
Reference Range:
43–159%
Comments:
The chromogenic factor VIII activity assay utilizes bovine factor X and human thrombin and factor IXa. It is insensitive to emicizumab, but may yield unreliable results in the presence of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban), high concentrations of heparin (>2 IU/mL), strong lupus anticoagulants (ratio >1.8), or the Mim8 bispecific antibody.
Methodology:
Chromogenic
CPT Code:
85130