C-Reactive Protein (CRP)

Label Mnemonic:	CRP
Epic code:	LAB149
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood from light green top tube or 1 light green Microtainer^® for pediatric patients

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

<0.5 mg/dL

Comments:

Refer to BD Microtainer^® Tubes product sheet for detailed sample collection instructions.

Test Limitations:

Criterion: Recovery within plus or minus 10% of initial values.

Icterus: No significant interference up to an I index of 60 
(approximate conjugated and unconjugated bilirubin concentration: 60 
mg/dL or 1026 μmol/l).

Hemolysis: No significant interference up to an H index of 1000. 
(approximate hemoglobin concentration: 1000 mg/dL).

Lipemia (Intralipid): No significant interference up to an L index of 
1000 (approximate triglyceride concentration: 2000 mg/dL or 22.8 
mmol/l).

There is poor correlation between turbidity and triglyceride 
concentration.

Rheumatoid factors less than 1200 IU/mL do not interfere.

A high-dose hook effect may occur at CRP concentrations greater than 
50 
mg/dL.

Significantly decreased CRP values may be obtained from samples taken 
from patients who have been treated with carboxypenicillins.

Methodology:

Immunoturbidimetric

CPT Code:

86140