Plasma

Call laboratory for additional acceptable specimen collection containers.

5 mL whole blood in light green top tube (adults) or TWO Microtainer^® devices (pediatric patients).

24 hrs/day, 7 days a week, including holidays.

1 hour (upon receipt in laboratory)

1.1-4.4 ng/mL in fasting specimens

Reference interval applies to fasting specimens. To convert to nmol/L, multiply ng/mL by 0.33.

This assay may be significantly impacted by high-dose biotin (>5 mg dose) taken within previous 12 hours. High concentrations of biotin may lead to falsely decreased results. These concentrations may be found in patients taking over-the-counter supplements with biotin content much higher than nutritional requirements for biotin. Specimens should not be collected until at least 12 hours after the last dose.

Fasting sample preferred.

Hemolysis: No significant interference up to an H index of 300 (approximate hemoglobin concentration: 300 mg/dL).

Lipemia: No significant interference up to an L index of 2000 (approximate triglycerides concentration: 4000 mg/dL). Note there is poor correlation between turbidity and triglyceride concentration.

Icterus: No significant interference up to an I index of 50 (approximate conjugated and unconjugated bilirubin concentration: 50 mg/dL).

Electrochemiluminescence Immunoassay

83519

See Additional Information:
Biotin Interference with Immunoassays