STAT6 Fusion (solitary fibrous tumor)
Label Mnemonic: SYTF
Epic Lab Code: LAB8313
Downtime Form: A-1a Molecular Pathology/Diagnostics Laboratory Requisition
Molecular Pathology
6004 BT GH
384-9568
Specimen(s):
Formalin Fixed, Paraffin Embedded Tissue Block
10 unstained 5-10 μM slides at 20-25°C and an H&E slide of the tissue 10 unstained 5-10 μM slides at 20-25°C and an H&E slide of the tissue
Minimum:
Tumor cells more than 50% of the total tissue and greater than 10mm2 in surface area on the block.
Rejection Criteria:
Specimens fixed in B5 fixative or that have been decalcified will not be accepted. Tumor specimens containing less than 50% tumor cells or are less than 10mm2 in area may be unacceptable.
Delivery Instructions:
Testing is generally not available on a STAT basis. However, expedited testing can be arranged by contacting the Molecular Pathology Laboratory at 384-9568.
Testing Schedule:
Weekly
Turn Around Time:
21 days
Comments:
RNA from FFPE tissue is used for amplification and massively parallel next generation sequencing to detect and identify STAT6 fusion transcripts derived from gene arrangements that are associated with extrapleural solitary fibrous tumor.
Methodology:
Massively parallel Next Generation RNA sequencing by synthesis, semiconductor technology, Ion Torrent, S5XL.
CPT Code:
81479