6004 BT GH
Formalin Fixed, Paraffin Embedded Tissue Block
10 unstained 5-10 μM slides at 20-25°C and an H&E slide of
Tumor cells more than 50% of the total tissue and greater than 10mm2
in surface area on the block.
Specimens fixed in B5 fixative or that have been decalcified will not
be accepted. Tumor specimens containing less than 50% tumor cells or
are less than 10mm2 in area may be unacceptable.
Testing is generally not available on a STAT basis. However, expedited
testing can be arranged by contacting the Molecular Pathology
Laboratory at 384-9568.
RNA from FFPE tissue is used for amplification and massively parallel
next generation sequencing to detect and identify EWSR1 fusion
transcripts derived from gene arrangements that are associated with
Ewing sarcoma, peripheral neuroectodermal tumor, clear cell sarcoma,
desmoplastic round cell tumor (DRCT) and extraskeletal myxoid
Massively parallel Next Generation RNA sequencing by synthesis,
semiconductor technology, Ion Torrent, S5XL.