Meningitis/Encephalitis Panel
Label Mnemonic: MENPANEL
Epic Lab Code: LAB8514
Downtime Form: A-1a Clinical Microbiology Laboratory Requisition
Microbiology
BT 6004
356-2591
Bacteriology/Virology Section
Specimen(s):
CSF, Lumbar puncture
Collection Medium:
CSF Collection Tubes
Minimum:
Collect in CSF container. A minimum volume of 1 mL CSF required in addition to volume required for other tests run on the same specimen. Transport to Microbiology Laboratory immediately.

•Cryptococcus PCR lacks sensitivity and cannot fully rule out
 cryptococcal meningitis; Cryptococcus antigen (Epic LAB2233) may be
 ordered if rapid testing is desired.
•Enterovirus testing includes Coxsackievirus A/B, Echovirus, and
 Enterovirus, including EV-D68, EV-D70 and EV-D71. Bacterial culture,
 Gram stain andsusceptibility testing are always performed with this order.
•Pretreatment may result in a PCR-positive, culture negative
 result.
•For interpretation of positive results, please see specific
 comments appended to individual patient reports.
Rejection Criteria:
CSF collected from indwelling medical devices are not acceptable, Aerobic culture (LAB4801) should be ordered for these specimen types.
Delivery Instructions:
Deliver to laboratory immediately after collection.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
6 hours (upon receipt in laboratory)
Reference Range:
Not Detected
Comments:
The FilmArray meningitis/encephalitis panel is a multiplex PCR test capable of qualitatively detecting DNA or RNA of 14 pathogens (bacteria and viruses).

The panel is used to diagnose infection caused by Escherichia coli, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus (includingCoxsackievirus A/B, Echovirus, and Enterovirus, including EV-D68, EV-D70 and EV-D71), Human herpesvirus 6 (HHV-6), Herpes simplex virus 1 (HSV-1), Herpes simples virus 2 (HSV-2), Human parechovirus, Varicella zoster virus, and Cryptococcus neoformans/gattii.
Methodology:
PCR amplification; FilmArray ME Panel
CPT Code:
87483