Commercial Mail-out Laboratory
Patient Prep: Diet, medication, and nutritional supplements may
introduce interfering substances. Patients should be encouraged to
discontinue nutritional supplements, vitamins, minerals, and non-
essential over-the-counter medications (upon the advice of their
physician). High concentrations of iodine may interfere with elemental
testing. Abstinence from iodine-containing medications or contrast
agents for at least 1 month prior to collecting specimens for
elemental testing is recommended.
|Urine (Random)-BD Vacutainer®, no additive yellow top
Preferred Minimum: 8 mL random urine
Absolute Minimum: 1 mL random urine
Urine collected within 48 hours after administration of a gadolinium
(Gd) containing contrast media (may occur with MRI studies). Acid
1-3 days upon receipt at reference laboratory
Copper, Urine - per volume: 0.3-3.2 μg/dL
Copper Urine - ratio to CRT: 10.0-45.0 μg/gCRT
Individuals with symptomatic Wilson disease usually excrete more than
100 copper per day. Other conditions associated with elevated urine
copper include cholestatic liver disease, proteinuria, some
medications, and contaminated specimens.
Although random specimens may contain diagnostic information, 24-hour
collection is a more consistent indicator of elevated copper.
Quantitative Inductively Coupled Plasma-Mass Spectrometry