Cadmium

Label Mnemonic:	CDUR
Epic code:	LAB8528
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Random Urine

Specimen Instructions:

Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non- essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.

Collection Medium:

Urine (Random)-BD Vacutainer^®, no additive yellow top

Minimum:

Preferred Minimum: 8 mL random urine
Absolute Minimum: 1 mL random urine

Rejection Criteria:

Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine.

Turn Around Time:

1-5 days upon receipt at reference laboratory

Reference Range:

Cadmium, Urine - per volume: 0.0-1.0 μg/L
Cadmium Rnd Urn ratio/CRT nonoccupation: 0.0-3.2 μg/gCRT

Interpretive Data:

Urine cadmium levels can be used to assess cadmium body burden. In chronic exposures, the kidneys are the primary target organ. Symptoms associated with cadmium toxicity vary based upon route of exposure and may include tubular proteinuria, fever, headache, dyspnea, chest pain, conjunctivitis, rhinitis, sore throat and cough. Ingestion of cadmium in high concentration may cause vomiting, diarrhea, salivation, cramps, and abdominal pain.

Methodology:

Quantitative Inductively Coupled Plasma-Mass Spectrometry

CPT Code:

82300