Cadmium
Label Mnemonic: CDUR
Epic Lab Code: LAB8528
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Random Urine
Specimen Instructions:
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non- essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.
Collection Medium:
Urine (Random)-BD Vacutainer®, no additive yellow top
Minimum:
Preferred Minimum: 8 mL random urine
Absolute Minimum: 1 mL random urine
Rejection Criteria:
Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine.
Testing Schedule:
1-3 days upon receipt at reference laboratory
Reference Range:
Cadmium, Urine - per volume: 0.0-1.0 μg/L
Cadmium Rnd Urn ratio/CRT nonoccupation: 0.0-3.2 μg/gCRT
Interpretive Data:
Urine cadmium levels can be used to assess cadmium body burden. In chronic exposures, the kidneys are the primary target organ. Symptoms associated with cadmium toxicity vary based upon route of exposure and may include tubular proteinuria, fever, headache, dyspnea, chest pain, conjunctivitis, rhinitis, sore throat and cough. Ingestion of cadmium in high concentration may cause vomiting, diarrhea, salivation, cramps, and abdominal pain.
Methodology:
Quantitative Inductively Coupled Plasma-Mass Spectrometry
CPT Code:
82300