C5-DC Acylcarnitine, Quantitative
| Label Mnemonic: | C5DCU |
| Epic code: | LAB8445 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Urine
Specimen
Instructions:
Include patient's age, family history, clinical condition
(asymptomatic or acute episode), diet, and drug therapy
information.
Collection Medium:
) |
| Yellow top round bottom tube (no additive) |
Minimum:
Preferred Minimim: 5 mL urine
Absolute Minimum: 1 mL urine
Absolute Minimum: 1 mL urine
Delivery Instructions:
Keep on ice and deliver to laboratory immediately.Turn Around
Time:
2 days upon receipt at reference laboratory (not reported on Sunday)
Reference Range:
<1.54 millimoles/mole creatinine
Interpretive Data:
Elevated excretion of C5-DC is a specific biochemical marker of
glutaric aciduria type 1 that is elevated in affected patients,
apparently even in low excretors or those affected individuals with
normal levels of glutaric acid in urine.
Comments:
Please print, complete and submit the Informed Consent for Genetic Testing from Mayo Medical Laboratories with the specimen.
Useful for:
Evaluation of patients with an abnormal newborn screen showing elevations of C5-DC
Diagnosis of glutaric aciduria type 1 deficiency
Cautions:
The results of urine acylcarnitines are not informative when the patient is receiving L-carnitine supplements.
Useful for:
Evaluation of patients with an abnormal newborn screen showing elevations of C5-DC
Diagnosis of glutaric aciduria type 1 deficiency
Cautions:
The results of urine acylcarnitines are not informative when the patient is receiving L-carnitine supplements.
Methodology:
Flow Injection Analysis-Tandem Mass Spectrometry (FIA-MS/MS)
CPT Code:
82017