AML Mutation Profiling and Interpretation
6004 BT GH
Testing requires dedicated collection tube.
|Pink top tube 6 mL (K2-EDTA)
2 mL peripheral blood in EDTA (pink tube).
Tumor specimens containing less than 20% tumor cells may be
The AML Mutation Profiling test is a massively parallel next
generation DNA sequencing-based assay that targets commonly mutated or
hotspot regions of 30 AML cancer-related genes.
NPM1, RUNX1, CEBPA, GATA2, KIT, CBL, JAK2, KRAS, NRAS, HRAS, BRAF,
TP53, PHF6, NF1, PTEN, PTPN11, WT1, DNMT3A, TET2, IDH1, IDH2, MLL,
ASXL1, EZH2, ZRSR2, SF3B1, SRSF2, U2AF1, SETBP1.
Massively parallel Next Generation DNA sequencing by synthesis,
semiconductor technology, Ion Personal Genomics Machine