Rufinamide Drug Level

Label Mnemonic:	RUFIN
Epic code:	LAB8346
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Specimen Instructions:

Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1.0 mL serum in red top tube
Absolute Minimum: 0.5 mL serum in red top tube

Rejection Criteria:

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Turn Around Time:

1-4 days upon receipt at reference laboratory

Reference Range:

Therapeutic Range                        5-30 µg/mL 

Dose-related range                       3-30 μg/mL 
(values at dosages of 800-7200 mg/day) 

Toxic                                    Not well established

Interpretive Data:

Adverse effects may include somnolence, vomiting, headache and fatigue.

Methodology:

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

CPT Code:

80210