Rufinamide Drug Level
Label Mnemonic: RUFIN
Epic code: LAB8346
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
Specimen Instructions:
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Collection Medium:
Red top tube 5 mL (Clot Activator)
Preferred Minimum: 1.0 mL serum in red top tube
Absolute Minimum: 0.5 mL serum in red top tube
Rejection Criteria:
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Turn Around Time:
1-4 days upon receipt at reference laboratory
Reference Range:
Therapeutic Range                        Not well established. 

Dose-​related range                       3-​30 μg/mL 
(values at dosages of 800-​7200 mg/day) 

Toxic                                    Not well established
Interpretive Data:
Adverse effects may include somnolence, vomiting, headache and fatigue.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
CPT Code: