RA Disease Activity
Label Mnemonic: RADA
Epic code: LAB8285
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
Whole Blood
Specimen Instructions:
Call Commercial Mailouts at 356-8593 for specimen collection kit.
Collection Medium:
Gold Top Tube from Vectra DA Kit
4 mL whole blood
Rejection Criteria:
Specimen not received at referral laboratory within 7 days of collection.
Delivery Instructions:
Deliver to laboratory immediately after collection.
Testing Schedule:
Monday - Friday only
Turn Around Time:
2 to 3 weeks upon receipt at reference laboratory
Reference Range:
Low 1 to 29
Moderate 30 to 44
High 45 to 100
Interpretive Data:
Vectra DA measures 12 biomarkers and combines them into a single disease activity score to assess the key mechanisms and pathways that drive rheumatoid arthritis (RA) disease activity. Measured biomarkers are adhesion molecule VCAM-1, growth factors EGF and VEGF-A, cytokine- related proteins IL-6 and TNF-RI, matrix metalloproteinases MMP-1 and MMP-3, skeletal-related protein YKL-40, hormones Leptin and Resistin, and acute phase proteins SAA and CRP. Clinical interpretation of individual biomarker levels, which have different weights in the Vectra DA algorithm, has not been established.

Vectra DA was validated in adults with RA. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with standard clinical assessment. This test is not intended or validated to diagnose RA.
For a Medicare patient, collect sample greater than 14 days after an inpatient discharge or an outpatient visit.

A completed, physician-signed test requisition must be submitted with sample and is available by calling Commercial Mailouts at 356- 8593.

Insurance information must be provided on the test requisition.

Crescendo CARE patient assistance program is available for all eligible commercial insurance and uninsured patients. Apply for financial assistance by completing the CARE form, available by calling Commercial Mailouts at 356-8583.
CPT Code:
83520 x 11, 86140