Amyloid Beta-Protein
Label Mnemonic: AMBETAPRO
Epic Lab Code: LAB8278
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
CSF
Specimen Instructions:
No specific patient preparation is required as Amyloid B-Protein is increased by the quantity and density of plaques.
Collection Medium:
Sterile container
Minimum:
Collect 2 mL CSF in sterile container.
Reference Range:
20- 80 pg/mL
Comments:
Amyloid B-Protein is a peptide that ranges in size from 28-43 amino acids. Most fragments have the same biological activity as the whole molecule. Amyloid B-Protein causes vascular and cerebral plaque formation. Insoluble fibrils of Amyloid B-Protein accumulate in adrenal blood vessels and un neutritic plaques. Occurrence of plaques are present in normal brain but in a much less dense degree as in Alzheimer's disease patients. Amyloid B-Protein is also found in elevated levels in patients with Down's Syndrome. Substance P has been found to counteract the effects of Amyloid B-Protein.

Amyloid Protein is measured by a specific radioimmunoassay procedure that measures all fragments from 1-40 amino acids.
CPT Code:
83519