Cancer Mutation Profiling and Interpretation
6004 BT GH
Bone Marrow Aspirate
Please provide the FFPE block or 10 unstained 5-10 μM slides with
an H&E slide of the tissue.
Testing requires dedicated collection tube.
|Lavender top tube 3 mL (EDTA)
2 mL Bone Marrow Aspirate in EDTA (lavender tube).
Specimens fixed in B5 fixative or decalcified will not be accepted.
Tumor specimens containing less than 20% tumor cells may be
The Cancer Mutation Profiling test is a massively parallel next
generation DNA sequencing-based assay that targets commonly mutated
or hotspot regions of 50 cancer-related genes.
Genes Assessed: ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A,
CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3,
FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR,
KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN,
RB1, RET, SMAD4, SMARC1, SMO, SRC, STK11, TP53, and VHL.
Massively parallel Next Generation DNA sequencing by synthesis,
semiconductor technology, Ion Personal Genomics Machine