Herpesvirus 7 (HHV-7) Quant Other
Label Mnemonic: HHV7O
Epic Lab Code: LAB7899
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Various Sample Types
Collection Medium:
Sterile container
Minimum:
Bronchial Lavage/Bronchial Wash: 2 mL, collected in sterile, screw-cap tube CSF: 2 mL submitted in sterile, screw-cap tube Tissue: Place a minimum of 5 mg fresh tissue (approximately 1/2 of a pencil eraser size) in a sterile, screw top container. Do not add water, saline or other fluid media to container. Formalin fixed, paraffin embedded tissue will not be accepted. Tracheal Aspirate/Tracheal Wash: 2 mL collected in a sterile, screw top tube
Rejection Criteria:
Whole blood frozen, specimens received in trap containers, or specimen types other than those listed.
Turn Around Time:
24 hours upon receipt in reference laboratory.
Reference Range:
Not Detected
Comments:
HHV-7 is detectable in a variety of transplant settings, both HSCT and solid organ. Direct effects of HHV-7 include fever, rash, myelosuppression, encephalitis, and pneumonitis. Potentially more important are the indirect effects HHV-7 has on CMV disease, invasive fungal disease, and allograft dysfunction. Quantitative HHV-7 DNA PCR can be used to document the presence of the virus as well as track the course of infection. The primers and probes used in this assay are specific for known strains of HHV-7 based on similarity search algorithms. Additionally, no cross reactivity was detected when tested against adenoviruses, BKV, CMV, EBV, HSV-1, HSV-2, HHV-6 variant A, HHV-6 variant B, HHV-8, JCV, parvovirus B19, SV-40, and VZV.
Methodology:
Quantitative Real-Time PCR
CPT Code:
87799