NMDA Receptor Antibodies
Label Mnemonic: NMDACSF
Epic Lab Code: LAB7731
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
CSF
Collection Medium:
CSF collection kit
Minimum:
Preferred Minimum: 1 mL CSF
Absolute Minimum: 0.15 mL CSF
Rejection Criteria:
Contaminated, hemolyzed, or severely lipemic specimens.
Turn Around Time:
1-8 days upon receipt at reference laboratory.
Reference Range:
< 1:1
Interpretive Data:
Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated to therapeutic response, therefore clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.
Comments:
NOTE: If NMDA CSF antibody IgG is positive, then an NMDA CSF antibody IgG titer will be added. Additional charges apply.
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody
CPT Code:
86255 NMDA IgG CSF; if reflexed add 86256 NMDA IgG CSF titer