Lead, Confirmation by ICP-MS
Label Mnemonic: LEADV
Epic Lab Code: LAB7479
Downtime Form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
Blood (Venous)
Specimen Instructions:
This test is for venous collection only. Capillary samples are NOT acceptable. Refer to the link below for Lead, Blood, by LeadCare II.
Collection Medium:
Lavender top tube 3 mL (EDTA)
Alternate Collection Media:
Royal Blue K2 EDTA tube
0.5 mL whole blood in lavender top tube
Rejection Criteria:
Heparin anticoagulant. Frozen specimens.
Turn Around Time:
1-2 days upon receipt at reference laboratory
Reference Range:
0.0-4.9 μg/dL

Concentration   Comment
5-9.9 μg/dL     Adverse health effects are possible, particularly
                in children under 6 years of age and pregnant women.
                Discuss health risks associated with continued lead 
                exposure. For children and women who are or may become
                pregnant, reduce lead exposure. 

10-19.9 μg/dL   Reduced lead exposure and increased biological
                monitoring are recommended. 

20-69.9 μg/dL   Removal from lead exposure and prompt medical
                evaluation are recommended. Consider chelation therapy 
                when concentrations exceed 50 μg/dL and symptoms 
                lead toxicity are present.

>69.9 μg/dL     Critical.  Immediate medical evaluation is
                recommended. Consider chelation therapy when symptoms 
                lead toxicity are present.
Interpretive Data:
Elevated results may be due to skin or collection-related contamination, including use of a noncertified lead-free tube. Elevated levels of blood lead should be confirmed with a second specimen collected in a lead-free tube.

Sources of reference interval and interpretive comments include the CDC Guidelines for Screening Children for Blood Lead, 1997 and the Recommendations for Medical Management of Adult Lead Exposure, Environmental Health Perspectives, 2007. Thresholds and time intervals for retesting, medical evaluation, and response vary by state and regulatory body. Contact your State Department of Health and/or applicable regulatory agency for specific guidance on medical management recommendations.
Expected turn-around time is 2-4 days. Please contact the Pathology Resident on-call (pager 3724) if more rapid testing is required for management of lead toxicity.
Quantitative Inductively Coupled Plasma/Mass Spectrometry
CPT Code:
See also:
Lead, Whole Blood, (By LeadCare)