Cobalt
Label Mnemonic: COS
Epic Lab Code: LAB7457
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Specimen Instructions:
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician).
Collection Medium:
Royal Blue top tube; serum, no additive
Minimum:
2 mL plasma from Royal Blue top tube (no additive)
Rejection Criteria:
Separator tubes and specimens that are not separated from the red cells, or clot, within 6 hours.
Turn Around Time:
1-5 days upon receipt at reference laboratory
Reference Range:
Less than or equal to 1.0 μg/L
Interpretive Data:
Serum cobalt levels can be used in the assessment of occupational exposure or toxic ingestion and is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty. Serum cobalt levels may be increased in asymptomatic patients with metal-on-metal prosthetics and should be considered in the context of the overall clinical scenario. Symptoms associated with cobalt toxicity vary based on route of exposure, and may include cardiomyopathy, allergic dermatitis, pulmonary fibrosis, cough and dyspnea.
Comments:
Royal Blue trace metal tube available from Specimen Control (356-3527) 6240 RCP.
Methodology:
Quantitative Inductively Coupled Plasma-Mass Spectrometry
CPT Code:
83018