Lamellar Body Count
Label Mnemonic: LBC
Epic Lab Code: LAB7446
Downtime Form: A-1a General Laboratory Requisition
Hematology
6240 RCP
356-3527
Specimen(s):
Amniotic Fluid
Specimen Instructions:
Sample should NOT be frozen.
Collection Medium:
Yellow top round bottom tube (no additive)
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
1 mL Amniotic Fluid
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
Percent Risk of Respiratory Distress Relative to Gestational
 Age (GA) and Lamellar Body Count of Amniotic Fluid
----------------------------------------------------
Lamellar body count         Weeks Gestation
  (#/μL x10-3)      34   35   36   37   38   39   40
----------------------------------------------------
        <16         74   72   71   70   68   67   66
      16-20         47   46   44   42   41   39   38
      21-25         33   31   30   28   27   26   25
      26-30         21   20   19   18   17   16   15
      31-35         12   12   11   10   10    9    9
      36-40          7    7    6    6    5    5    5
      41-45          4    4    3    3    3    3    3
      46-50          2    2    2    2    2    2    1
      51-55          1    1    1    1    1    1    1
      56-60         <1   <1   <1    1    1   <1   <1
      61-65         <1   <1   <1   <1   <1   <1   <1
      66-70         <1   <1   <1   <1   <1   <1   <1

From: Karcher R, Sykes E, Batton D, Uddin Z, Ross G, Hockman E,
Shade GH Jr.  Gestational age-specific predicted risk of neonatal
respiratory distress syndrome using lamellar body count and
surfactant-to-albumin ratio or amniotic fluid.  Am J Obstet 
Gynecol 193(5):1680-1684, 2005.
Comments:
If amniotic fluid contains meconium or blood, the LBC is cancelled.

This test replaces the "Fetal Lung Maturity" test.
Methodology:
Flow cytometry
CPT Code:
83664