Lamellar Body Count
Label Mnemonic: LBC
Epic code: LAB9202
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mailout Laboratory
6240-8 RCP
356-8593
Specimen(s):
Amniotic Fluid
Specimen Instructions:
Sample should NOT be frozen.
Collection Medium:
Yellow top round bottom tube (no additive)
Minimum:
2 mL Amniotic Fluid
Testing Schedule:
24 hours upon receipt at reference laboratory.
Turn Around Time:
24 hours upon receipt at reference laboratory (upon receipt in laboratory)
Reference Range:
Immature: <15,000/mcL
Indeterminate: 15,000-50,000/mcL
Mature: >50,000/mcL

Cutoffs are based on consensus protocol (Neerhof M, Dohnal JC, Ashwood ER, et al: Lamellar body counts: a consensus on protocol. Obstet Gynecol. 2001;97:318-320)
Interpretive Data:
Amniotic fluid lamellar body counts (LBC) above 50,000/mcL are predictive of fetal lung maturity.

Amniotic fluid LBC below 15,000/mcL are suggestive of fetal lung immaturity and increased risk of neonatal respiratory distress syndrome (RDS).

The main value of fetal lung maturity testing is predicting the absence of RDS. An immature test result for fetal lung maturity is less reliable in predicting the presence of RDS.(1)
Comments:
If amniotic fluid contains meconium or blood, the LBC is cancelled.

This test replaces the "Fetal Lung Maturity" test.
Methodology:
Impedance
CPT Code:
83664