Homovanillic Acid
| Label Mnemonic: | HVAUR |
| Epic code: | LAB7403 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Random Urine
Collection Medium:
) |
| Yellow top round bottom tube (no additive) |
Minimum:
Preferred Minimum: 4 mL random urine
Absolute Minimum: 1 mL random urine
Abstain from medications for 72 hours prior to collection.
Absolute Minimum: 1 mL random urine
Abstain from medications for 72 hours prior to collection.
Turn Around
Time:
1-5 days upon receipt at reference laboratory
Reference Range:
Components Age Ref. Interval
HVA, Urine 18 years and older 0.0-15.0 mg/d
HVA 0-2 years 0-42 mg/g CRT
3-5 years 0-22 mg/g CRT
6-17 years 0-15 mg/g CRT
18 years and older 0-8 mg/g CRTInterpretive Data:
Homovanillic acid (HVA) results are expressed as a ratio to creatinine
excretion (mg/g cr). HVA mass per day (mg/d) is not reported on
specimens from patients younger than 18 years of age, for random
specimens, urine collection periods other than 24 hours, or for urine
volumes less than 400 mL/d. No reference interval is available for
results reported in units of mg/L.
Comments:
Moderately elevated HVA (homovanillic acid) may be caused by a variety
of factors such as essential hypertension, intense anxiety, intense
physical exercise, and numerous drug interactions (including some over-
the-counter medications and herbal products).
Medications which may interfere with catecholamines and their metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, chlorpromazine, clonidine, disulfiram, diuretics (in doses sufficient to deplete sodium), epinephrine, glucagon, guanethidine, histamine, hydrazine derivatives, imipramine, levodopa (L-dopa, Sinemet®), lithium, MAO inhibitors, melatonin, methyldopa (Aldomet®), morphine, nitroglycerin, nose drops, propafenone (Rythmol), radiographic agents, rauwolfia alkaloids (Reserpine), and vasodilators. The effects of some drugs on catecholamine metabolite results may not be predictable.
Medications which may interfere with catecholamines and their metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, chlorpromazine, clonidine, disulfiram, diuretics (in doses sufficient to deplete sodium), epinephrine, glucagon, guanethidine, histamine, hydrazine derivatives, imipramine, levodopa (L-dopa, Sinemet®), lithium, MAO inhibitors, melatonin, methyldopa (Aldomet®), morphine, nitroglycerin, nose drops, propafenone (Rythmol), radiographic agents, rauwolfia alkaloids (Reserpine), and vasodilators. The effects of some drugs on catecholamine metabolite results may not be predictable.
Methodology:
Quantitative High Performance Liquid Chromatography-Tandem Mass
Spectrometry
CPT Code:
83150
See also:
Catecholamines, Fractionated, Random Urine
Metanephrines Total, Random Urine
Vanillylmandelic Acid, Random Urine
Catecholamines, Fractionated, Random Urine
Metanephrines Total, Random Urine
Vanillylmandelic Acid, Random Urine
See Additional Information:
Urine Tests Requiring no Preservatives
Urine Tests Requiring no Preservatives