Anti-Mullerian Hormone
Label Mnemonic: AMH
Epic Lab Code: LAB7364
Downtime Form: A-1a Miscellaneous Request
Chemistry
6240 RCP
356-3527
Specimen(s):
Blood
Collection Medium:
Plasma Separator Tube 4.5 mL
Minimum:
3 mL in light green top tube or TWO Microtainer® devices
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
  Sex / Age Reference Range Females / 20 up to 25 1.22-11.7 ng/mL Females / 25 up to 30 0.890-9.85 ng/mL Females / 30 up to 35 0.576-8.13 ng/mL Females / 35 up to 40 0.147-7.49 ng/mL Females / 40 up to 45 0.030-5.47 ng/mL
Interpretive Data:
Menopausal women or women with premature ovarian failure of any cause (including after cancer chemotherapy) will generally have very low antimüllerian hormone (AMH), often below the lower detection limit of quantification (0.03 ng/mL). In women with polycystic ovarian syndrome, AMH concentrations may be two- to five-fold higher than age-appropriate reference intervals. Reference ranges for females less than 20 years old have not been established for this assay. AMH concentrations in women typically reach peak values between 18-25 years old.

Reference ranges for males have not been established for this assay. However, AMH concentration in boys up through 12 years old are generally much higher than those found in adult females. In boys with cryptorchidism, a measurable AMH concentration is predictive of undescended tests, while an undetectable value is suggestive of anorchia or functional failure of the abnormally sited gonad.
Methodology:
Electrochemiluminescence Immunoassay (ECLIA)
CPT Code:
83520