Busulfan Drug Level
Label Mnemonic: BUS
Epic code: Lab5829
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Whole Blood
Specimen Instructions:
Specimens must be received at reference laboratory by 11:00 a.m. 
to be analyzed the same day.

Exact collection times must be written on tubes.

Specimen must be placed in wet ice immediately after collection and 
then delivered immediately to Specimen Control.

Note:  Collection time refers to time AFTER COMPLETION of IV 
infusion.  Drug typically infused for 120 minutes (2 hours).

For Dose 1 only - end of infusion, 15 minutes, 30 minutes, 1 hour, 2 
hours, 3 hours, 4 hours and 6 hours.

For follow-up doses - pre infusion (just prior to start of IV), end of 
infusion, 15 minutes, 30 minutes, 2 hours and 4 hours.
Collection Medium:
Green top tube 4 mL (Na Heparin)
Minimum:
Preferred Minimum: 4 mL whole blood (sodium heparin)
Absolute Minimum: 1 mL whole blood (sodium heparin)
Delivery Instructions:
Keep on ice and deliver to laboratory immediately. Test must be scheduled 72 hours in advance with reference laboratory. Call Commercial Mailouts to schedule (6-8593).
Testing Schedule:
Daily when scheduled.
Turn Around Time:
24 hours upon receipt at reference laboratory (upon receipt in laboratory)
Reference Range:
By report
Comments:
IV Busulfan Pharmacokinetics form, completed by clinical staff, must be submitted with final specimen.
Methodology:
GC Mass Spectrometry
CPT Code:
83789