Busulfan Drug Level

Label Mnemonic:	BUS
Epic code:	LAB5829
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Whole Blood

Specimen Instructions:

Specimens must be received at reference laboratory by 11:00 a.m. 
to be analyzed the same day.

Exact collection times must be written on tubes.

Specimen must be placed in wet ice immediately after collection and 
then delivered immediately to Specimen Control.

Note:  Collection time refers to time AFTER COMPLETION of IV 
infusion.  Drug typically infused for 120 minutes (2 hours).

For Dose 1 only - end of infusion, 15 minutes, 30 minutes, 1 hour, 2 
hours, 3 hours, 4 hours and 6 hours.

For follow-up doses - pre infusion (just prior to start of IV), end of 
infusion, 15 minutes, 30 minutes, 2 hours and 4 hours.

Collection Medium:

Green top tube 4 mL (Na Heparin)

Minimum:

Preferred Minimum: 4 mL whole blood (sodium heparin)
Absolute Minimum: 1 mL whole blood (sodium heparin)

Delivery Instructions:

Keep on ice and deliver to laboratory immediately. Test must be scheduled 72 hours in advance with reference laboratory. Call Commercial Mailouts to schedule (6-8593).

Testing Schedule:

Daily when scheduled.

Turn Around Time:

24 hours upon receipt at reference laboratory (upon receipt in laboratory)

Reference Range:

By report

Comments:

IV Busulfan Pharmacokinetics form, completed by clinical staff, must be submitted with final specimen.

Methodology:

GC Mass Spectrometry

CPT Code:

80375