Heat Shock Protein 70 (68 kDa), IgG
Label Mnemonic: HSP
Epic Lab Code: LAB7249
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Preferred Minimum: 0.5 mL serum
Absolute Minimum: 0.1 mL serum
Rejection Criteria:
Urine or plasma. Heat inactivated and contaminated specimens.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.
Turn Around Time:
1-4 days upon receipt at reference laboratory
Reference Range:
Negative
Interpretive Data:
The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.
Methodology:
Qualitative Immunoblot
CPT Code:
83516