Heat Shock Protein 70 (68 kDa), IgG

Label Mnemonic:	HSP
Epic code:	LAB7249
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 0.5 mL serum
Absolute Minimum: 0.1 mL serum

Rejection Criteria:

Urine or plasma. Heat inactivated and contaminated specimens.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Testing Schedule:

Test performed on Thursdays.

Turn Around Time:

1-8 days upon receipt at reference laboratory

Reference Range:

Negative

Interpretive Data:

The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.

Methodology:

Qualitative Immunoblot

CPT Code:

83516