KRAS Gene Analysis Variants in codons 12 and 13 and Exon 3 with Interpretation
Label Mnemonic: KRAS
Epic Lab Code: LAB5763
Downtime Form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Molecular Pathology
6004 BT GH
Formalin fixed, paraffin embedded tissue block and 10 unstained 5-10 μM slides at 20-25°C and an H&E slide of the tissue
Tumor cells more than 50% of the total tissue and greater than 10mm2 in surface area on the block.
Rejection Criteria:
Specimens fixed in B5 fixative or that have been decalcified will not be accepted. Tumor specimens containing less than 50% tumor cells or are less than 10mm2 in area may be unacceptable.
Testing Schedule:
Turn Around Time:
7-10 working days
Reference Range:
The tissue will be reviewed by a pathologist prior to testing to identify that it contains at least 50% tumor.

This assay detects mutations in codons 12, 13 and 61 (19 mutations in total).
Polymerase Chain Reaction and Single Nucleotide Primer Extension. Massively parallel Next Generation DNA sequencing by synthesis, semiconductor technology, Ion Personal Genomics Machine.
CPT Code: