|Downtime form:||A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery|
|Plasma Separator Tube 4.5 mL|
Ordinarily, β-hydroxybutyrate is the ketoacid present in the greatest amount in serum. It accounts for approximately 75% of the ketone bodies which also include acetoacetate and acetone. During periods of ketosis, β-hydroxybutyrate increases even more than the other two keto acids (acetoacetate and acetone), and has been shown to be a good index of ketoacidosis, including the detection of subclinical ketosis.
In diabetics, the measurement of β-hydroxybutyrate as well as blood glucose can help to assess the severity of diabetic coma and help exclude hyperosmolar non-ketotic diabetic coma.
The β-hydroxybutyrate assay is specific for β-hydroxybutyrate and shows no cross-reactivity with acetoacetate or acetone.