Soluble Liver Antigen Ab, IgG
Label Mnemonic: SLA
Epic Lab Code: LAB4480
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Preferred Minimum: 1 mL serum
Absolute Minimum: 0.3 mL serum
Rejection Criteria:
Hemolyzed, lipemic, contaminated, or heat-inactivated specimens.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.
Turn Around Time:
1-4 days upon receipt at reference laboratory
Reference Range:
0.0-20.0 U: Negative
20.1-24.9 U: Equivocal
Greater than or equal to 25.0 U: Positive
Interpretive Data:
The presence of SLA antibodies has almost 100% specificity for autoimmune hepatitis, although only 12-30% have these antibodies. Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
CPT Code:
83516