Dengue Fever Virus Ab, IgG

Label Mnemonic:	DENG
Epic code:	LAB2989
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1.0 mL serum
Absolute Minimum: 0.1 mL serum

Rejection Criteria:

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection period is completed.

Turn Around Time:

1-4 days upon receipt at reference laboratory

Reference Range:

1.64 IV or less: Negative - No significant level of detectable dengue
                            fever virus IgG antibody.

1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat
                          testing in 10-14 days may be helpful.

2.85 IV or greater: Positive - IgG antibody to dengue fever virus
                               detected, which may indicate a current
                               or past infection.

Interpretive Data:

Patients in the early stage of dengue fever virus infection may not have detectable IgG antibodies, as the IgG response may take several weeks to develop. In the absence of detectable IgG, testing for IgM class antibody is strongly recommended. The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Comments:

Acute and convalescent specimens must be labeled as such parallel testing is preferred and convalescent sample must be received within 30 days of acute.

Methodology:

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

CPT Code:

86790