Dengue Fever Virus Ab, IgM

Label Mnemonic:	DENM
Epic code:	LAB2990
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1.0 mL serum
Absolute Minimum: 0.1 mL serum

Rejection Criteria:

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection period is completed.

Turn Around Time:

1-5 days upon receipt at reference laboratory

Reference Range:

1.64 IV or less: Negative - No significant level of detectable dengue
                            fever virus IgM antibody.

1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat
                          testing in 10-14 days may be helpful.

2.85 IV or greater: Positive - IgM antibody to dengue fever virus
                               detected, which may indicate a current
                               or recent infection.

However, low levels of IgM antibodies may occasionally persist for more 
than 12 months post-infection.

Interpretive Data:

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Comments:

Acute and convalescent specimens must be labeled as such; parallel testing preferred. Convalescent sample must be received within 30 days of acute specimens.

Methodology:

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

CPT Code:

86790