Sertraline (Zoloft) Drug Level
| Label Mnemonic: | SERT |
| Epic code: | LAB4045 |
| Downtime form: | A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Serum
Specimen
Instructions:
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Collection Medium:
 |
| Red top tube 5 mL (Clot Activator) |
Minimum:
Preferred Minimum: 1 mL serum
Rejection Criteria:
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS
or ACD solution).
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.Testing Schedule:
Wednesdays
Turn Around
Time:
1-8 days upon receipt at reference laboratory.
Reference Range:
Therapeutic Range: Not well established. Toxic: > 300 ng/mL
Interpretive Data:
Sertraline doses ranging from 50-200 mg/d produce serum concentration
ranging from 30-200 ng/mL. Dosing above 200 mg/d is associated with
increased adverse effects and decreased efficacy. Adverse effects may
include dry mouth, headache, dizziness, somnolence, nausea and diarrhea.
Methodology:
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
CPT Code:
80332