Herpes Virus 7 (HHV-7) Quant.
Label Mnemonic: HHV7
Epic Lab Code: LAB3315
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Plasma
Collection Medium:
Pink top tube 6 mL (K2-EDTA)
Alternate Collection Media:
Lavender top tube 3 mL (EDTA)
Minimum:
2 mL plasma collected in EDTA (pink top) tube
Rejection Criteria:
Whole blood frozen.
Turn Around Time:
24 hours upon receipt in reference laboratory.
Reference Range:
Not detected.
Comments:
HHV-7 is detectable in a variety of transplant settings, both HSCT and solid organ. Direct effects of HHV-7 include fever, rash, myelosuppression, encephalitis, and pneumonitis. Potentially more important are the indirect effects HHV-7 has on CMV disease, invasive fungal disease, and allograft dysfunction. Quantitative HHV-7 DNA PCR can be used to document the presence of the virus as well as track the course of infection. The primers and probes used in this assay are specific for known strains of HHV-7 based on similarity search algorithms. Additionally, no cross reactivity was detected when tested against adenoviruses, BKV, CMV, EBV, HSV-1, HSV-2, HHV-6 variant A, HHV-6 variant B, HHV-8, JCV, parvovirus B19, SV-40, and VZV.
Methodology:
Quantitative Real-Time PCR
CPT Code:
87799