Neuron Specific Enolase, CSF
Label Mnemonic: NSECSF
Epic code: LAB3701
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Spinal Fluid
Collection Medium:
CSF collection kit
Minimum:
Requested Minimum:  0.5 mL CSF
Absolute Minimum:  0.3 mL CSF
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.
Turn Around Time:
4 days upon receipt in reference laboratory
Reference Range:
Normal: <=15 ng/mL
Indeterminate: 15-30 ng/mL
Elevated: >30 ng/mL
Elevated results may indicate the need for additional work-up.  
Possible causes may be NSE-secreting CNS/Leptomeningeal tumor or rapid 
neuronal destruction from a variety of causes. In the context of 
dementia, elevated results may be suggestive of Creutzfeldt-Jakob 
disease.
Methodology:
Homogeneous Time Resolved Fluorescence (HTRF) on the BRAHMS Kryptor Compact
CPT Code:
83520