Neuron Specific Enolase, CSF

Label Mnemonic:	NSECSF
Epic code:	LAB3701
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Spinal Fluid

Collection Medium:

CSF collection kit

Minimum:

Requested Minimum:  0.5 mL CSF
Absolute Minimum:  0.3 mL CSF

Delivery Instructions:

Submit specimen to laboratory as soon as possible after collection.

Turn Around Time:

4 days upon receipt in reference laboratory

Reference Range:

Normal: <=15 ng/mL
Indeterminate: 15-30 ng/mL
Elevated: >30 ng/mL
Elevated results may indicate the need for additional work-up.  
Possible causes may be NSE-secreting CNS/Leptomeningeal tumor or rapid 
neuronal destruction from a variety of causes. In the context of 
dementia, elevated results may be suggestive of Creutzfeldt-Jakob 
disease.

Methodology:

Homogeneous Time Resolved Fluorescence (HTRF) on the BRAHMS Kryptor Compact

CPT Code:

83520