Lorazepam Drug Level

Label Mnemonic:	LORAZ
Epic code:	LAB3519
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum or Plasma

Specimen Instructions:

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 2.0 mL serum
Absolute Minimum: 1.0 mL serum

Rejection Criteria:

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate).

Delivery Instructions:

Deliver to laboratory within 1 hour of collection.

Turn Around Time:

1-5 days upon receipt at reference laboratory

Reference Range:

Dose-Related Range:
  50 - 240 ng/mL - Dose (Adult): 1-10 mg/d
  Toxic: > 300 ng/mL

Interpretive Data:

Adverse effects may include respiratory depression, sedation, dizziness, weakness and lethargy.

Comments:

Avoid use of separator tubes and gels.

Methodology:

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

CPT Code:

80346