Strongyloides Antibody, IgG by ELISA
Commercial Mail-out Laboratory
|Red top tube 5 mL (Clot Activator)
Preferred Minimum: 1.0 mL serum in red top tube
Absolute Minimum: 0.05 mL serum in red top tube
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, or
1-8 days upon receipt at reference laboratory
1.49 IV or less: Negative
No significant level of Strongyloides IgG antibody detected.
1.50 - 2.10 IV: Equivocal
Questionable presence of Strongyloides IgG antibody detected.
Repeat testing in 10 - 14 days may be helpful.
2.11 IV or greater: Positive
IgG antibodies to Strongyloides detected, which may suggest
current or past infection.
This assay should be used to aid in the diagnosis and confirmation of
patients in which there is a clinical suspicion of Strongyloides
infection. Results for this test should not be used without correlation
to clinical history or other data.
This assay will detect the presence of serum IgG antibodies against
Strongyloides species. While diagnosis may be made clinically,
serologic antibody testing can aid in the diagnosis of
Strongyloidiasis. However, cutaneous larva migrans is observed with
infections by other nematodes such as Ancylostoma species, Uncinaria
stenocephala, and Bunostomum phlebotomum. Additionally, antibody
cross-reactions in patients with filariasis may occur.
The enzyme immunoassay for Strongyloides antibody detection is
recommended in place of IFA or IHA due to its sensitivity, which ranges
from 84-92 percent. However, eight to 16 percent of individuals
infected with Strongyloides are seronegative, so false-negative results
cannot be ruled out. Additionally, since this assay measures
Strongyloides-specific IgG in patient samples, test results from single
samples cannot be used to differentiate between current and past
Semi-Quantitative Enzyme-Linked Immunosorbent Assay