ABL1 Gene Analysis Kinase Variants
Label Mnemonic: BCRSQ
Epic Lab Code: LAB7394
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Whole Blood or Bone Marrow
Collection Medium:
or
Pink top tube 6 mL (K2-EDTA) Lavender top tube 3 mL (EDTA)
Minimum:
5 mL whole blood (ONE pink top tube) or 3 mL bone marrow (ONE lavender top tube)
Rejection Criteria:
Serum or plasma. Specimens collected in anticoagulants other than EDTA. Frozen Specimens. Clotted or serverely hemolyzed specimens.
Delivery Instructions:
Deliver to laboratory immediately after collection. Sample is only viable for 48 hours. Collect Monday through Thursday only; do not collect on Fridays, holidays, day before a holiday, or weekends.
Turn Around Time:
10-12 days upon receipt at reference laboratory.
Reference Range:
By report.
Interpretive Data:
Refer to report.
Comments:
Determine if a mutation is present that would interfere with response to TKI therapy in Philadelphia chromosome positive (Ph+) lymphoblastic leukemia or chronic myelogenous leukemia (CML). Test detects all common mutations, including T315I.
Methodology:
Massively Parallel Sequencing
CPT Code:
81479
 
See Additional Information:
Specimens Requiring Immediate Delivery