Thyroid Stimulating Immunoglobulin (TSH receptor antibodies)

Label Mnemonic:	TSI
Epic code:	LAB4165
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1.0 mL serum
Absolute Minimum: 0.5 mL serum

Rejection Criteria:

Plasma

Turn Around Time:

Within 24 hours upon receipt at reference laboratory

Reference Range:

0.54 IU/L or less - Consistent with healthy thyroid function or 
                    non-Graves thyroid or autoimmune disease. Those
                    with healthy thyroid function typically have
                    results less than 0.1 IU/L.

0.55 IU/L or greater - Consistent with Graves disease (autoimmune
                       hyperthyroidism).

Interpretive Data:

This assay specifically detects thyroid stimulating autoantibodies. For diagnostic purposes, the results obtained from this assay should be used in combination with clinical examination, patient medical history, and other findings.

Methodology:

Semi-Quantitative Chemiluminescent Immunoassay

CPT Code:

84445