Tetanus Antibody, IgG
Label Mnemonic: TETNUS
Epic Lab Code: LAB4144
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
Specimen Instructions:
"Pre" and "post" vaccine specimens can be submitted separately or together for testing; if shipped separately, "post" specimen must be received within 60 days of "pre" specimen. Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine".
Collection Medium:
Red top tube 5 mL (Clot Activator)
Preferred Minimum: 1.0 mL serum in a red top tube
Absolute Minimum: 0.2 mL serum in a red top tube
Rejection Criteria:
Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
Delivery Instructions:
Submit specimen to laboratory as soon as possible after collection.
Turn Around Time:
1-2 days upon receipt at reference laboratory
Reference Range:
Antibody concentration of > 0.1 IU/mL is usually considered protective.
Interpretive Data:
Responder status is determined according to the ratio of a one- month post-vaccination sample to pre-vaccination concentration of Tetanus IgG Abs as follows: 1. If the post-vaccination concentration is less than 1.0 IU, the patient is considered a nonresponder. 2. If the post-vaccination concentration is greater than or equal to 1.0 IU, a patient with a ratio of less than 1.5 is a nonresponder, a ratio of 1.5 to less than 3.0, a weak responder, and a ratio of 3.0 or greater, a good responder. 3. If the pre-vaccination concentration is greater than 1.0, it may be difficult to assess the response based on a ratio alone. A post-vaccination concentration above 2.5 IU in this case is usually adequate.
Include patient immunization status (pre or post immunization) on requisition. Analysis includes both the Pre and Post status if paired specimens were submitted. Serum must be removed from cells as soon as possible after blood draw.
Quantitative Multiplex Bead Assay
CPT Code: