Protein C, Functional
Label Mnemonic: PCFX
Epic code: LAB1133
Downtime form: Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Hemostasis/Thrombosis
6240 RCP
356-3573
Specimen(s):
Plasma More information
Collection Medium:
Light Blue top tube 2.7 mL (Na Citrate)
Minimum:

Full draw; 2.7 mL light blue top

Rejection Criteria:

Short drawn tube, clot, traumatic tap (excessive hemolysis).

Testing Schedule:
0800-1630 Monday, Wednesday and Friday. If you need results STAT, call Hematology resident (0800-1630, M-F) at 356-8628. All other times page the Pathology resident on-call at 3404.
Turn Around Time:

1-3 days upon receipt in laboratory

Reference Range:

>=83%

Interpretive Data:

Patients on warfarin may have decreased protein C levels. Warfarin therapy should be discontinued for at least two weeks prior to protein C testing. Decreased concentrations of protein C are also associated with liver disease, vitamin K deficiency, acute thrombosis, and DIC. Increased protein C concentrations may be observed in nephrotic syndrome, pregnancy, and with estrogen therapy.

Reference range updated 9/22/2020.

Methodology:

Activity detection by chromogenic substrate.

CPT Code:
85303
 
See Additional Information:
Thrombotic Evaluation
Phlebotomy Tubes and Order of Draw
Hemolysis Chart
Impact of Common Anticoagulants on Coagulation Tests