Primidone And Metabolite Drug Level
Label Mnemonic: PRIM
Epic code: LAB485
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Plasma
Collection Medium:
Green top tube 4 mL (Na Heparin)
Minimum:
Preferred Minimum:  1 mL plasma
Absolute Minimum:  0.8 mL plasma
Rejection Criteria:
Separator tubes
Turn Around Time:
24 hours upon receipt at reference laboratory (upon receipt in laboratory)
Reference Range:
Phenobarbital      0-2 months: 15.0-30.0 μg/mL
                     Toxic: 40.1 μg/mL or greater
                   3 months and older: 15.0-40.0 μg/mL
                     Toxic: 50.1 μg/mL or greater

Primidone          5-12 μg/mL
Interpretive Data:
Primidone concentrations greater than 15 μg/mL in conjunction with therapeutic levels of phenobarbital may be associated with toxicity.
Methodology:
Immunoassay
CPT Code:
80188 Primidone; 80184 Phenobarbital